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http://www.psychonaut.com/index.php?opt ... tp&lang=fr
http://www.psychonaut.com/index.php?opt ... tp&lang=fr
Sinon en anglais:
1. MDMA speeds up serotonin and dopamine release and use.
2. you get high
3. serotonin runs out
4. dopamine goes where serotonin normally would.
5. oxidized dopamine molecules cause damage to nerves.
6. The higher your serotonin levels are before you Roll,
the less dopamine will become oxidized.
7. The less dopamine in your system the less the chance of
oxidized dopamine forming.
Ingredients Needed
* MDMA
* Rolaids
* Grapefruit juice
* Prozac
* Vitamin B-6
* Vitamin C
* 5-HTP
* DLPA
* L-Glutamine
* Magnesium
Time Line
* Day 01 - Preload
* Day 02 - Preload
* Day 03 - Preload
* Day 04 - Drop
* Day 05 - Post Load -- this is when you get home from the party before passing out/going to sleep
* Day 06 - Post Load
Preload
It is best to space out amino acid intake to minimize competition between them. for maximum absorbance take with something sugary preferably grapefruit juice. Also when dealing with amounts try to keep constancy, if you take the lowest amount for one take the lowest amount for all. I recommend taking the lowest amount of each because the rest will most likely just be flushed from your body without being used.
500-1000mg Magnesium
500-1000 L-Glutamine
Grapefruit juice
Wait 1 hour or more
500-2000 DLPA
Grapefruit juice
Wait 1 hour or more and Before Going to sleep
100-200mg 5-HTP
25-50mg Vitamin B-6
200-1000mg Vitamin C
Grapefruit juice
Drop
Try to relax as much as possible and get yourself in a good mood for the trip ahead.
* Go out and eat a good meal consisting of fish and lots of green vegetables, since you won't eat for like 24 hours probably.
* Don't eat 5-6 hours prior to dropping -- you want an "empty stomach" so the pill takes effect quicker and more efficiently
* Take some Rolaids/Tums to neutralize your tummy about an hour before dropping, or at the same time as your drop -- this helps with prolonging your roll since less of the pill is being dissolved by stomach acids as well as wards of any nausea feelings
* after dropping, stay warm and active. sitting around will make the roll come on slower and weaker. moving around/dancing helps to get it in your blood and to your brain quicker. the cold will just kill your roll.
* some people i know like to chew the pill to break it down and help come on quicker and more intense. i find this makes me nauseus sometimes since it's sooo much at once (and it tastes like ass).
* Drink water, but not too much water. You can over-hydrate which will thin your blood and could cause death or screw up the saline content ratio, just as much as you can over-heat and dehydrate. Be smart. In addition to drinking water, drink other fluids, especially things designed to replenish you. Gatoraid and other sports drinks work well. A little known secret is that "Pediatric Electrolyte" formulas work as that is what they're designed for. Get them in the baby isle of any supermarket for about $5/liter -- plus it goes with the whole Candy Raver/Pacifier thing ;-)
* Also, force yourself to urinate every few hours -- you will forget to do this and your bladder will be full.
100mg 5-HTP
25mg Vitamin B-6
200mg Vitamin C
Grapefruit juice
2-4 Rolaids
500-2000 DLPA
MDMA
Drink water, but not too much!
Before Going to sleep
100mg 5-HTP
25mg Vitamin B-6
200mg Vitamin C
Grapefruit juice
Postload
If you have PROZAC take a regular dose about 4 hours after you have taken MDMA, Prozac has been proven to prevent neurotoxicity, by preventing the creation of Oxidized Dopamine.
Before Going to sleep
100-200mg 5-HTP
25-50mg Vitamin B-6
200-1000mg Vitamin C
Grapefruit juice
avec quelques rectification de Gradient:
I think there may be a few issues with this guide to safe consumption; some of the assumed biochemical relationships between some of these supplements and the activity of MDMA are theoretical at best, and contentious to say the least.
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1. How does dopamine go where serotonin normally would? Is this referring to 5-HT receptors or the cystol of surrounding serotonergic cells? Both aren't likely.
2. I'd question whether an acute administration of any SSRI would be a desirable method of coping with the recovery from an MDMA experience. Many individuals report extremely unpleasant effects from the first few days of SSRI therapy, and most individuals that ingest SSRIs who don't suffer from depression are extremely aversive to the drugs. If this is a method of raising serotonergic activity after the MDMA experience - it's better to leave it to the brain in this case, as substituting one drug for another to foster neurotransmitter activity isn't generally preferable.
3. What is the value of L-Glutamine here?
4. Taking Vitamin C for it's antioxidant properties isn't the most effective alternative to pursue. Other supplement-antioxidants like r-ala or gliSODin might prove more effective to prevent oxidative damage derived from MDMA intake.
5. Taking Phenylalanine (assumedly as a precursor to norepinephrine and dopamine) isn't recommended as a means of enhancing pleasurable dopaminergic activity. The inevitably enhanced norepinephrine activity is almost unavoidably going to generate anxiety and a persistent alertness. Such supplementation might contribute to a negative experience, or 'immediate crash'.
6. Repeated exposure to the enzymatic inhibitors present in grapefruit juice will be counterproductive in the days prior to an MDMA experience. This wont serve to inhibit the activity of these enzymes; rather, the enzymes will undergo a process known as enzyme induction, and will be produced in higher quantities. This means that more of the MDMA will be metabolized into biologically inert molecules, with no enjoyable psychoactivity. This probably isn't a viable method of enhancing sensitivity to MDMA, but it will indeed render an individual a more effective metabolizer of MDMA - which will reduce the overal potency of the chemical at the brain.
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Aside from those points, the B-6 is likely a good idea to prevent painful muscle cramps after the experience. The routine 5-HTP administration during the 'Preloading' days is questionable in its efficacy, as excess serotonin wont necessarily lead to a more enjoyable overall experience.
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