reverse tolerance

[gayedohi]

does anyone know if the reverse tolerance effect is permanent or if you don't do it for awhile you have to start over?

 

[Pariah]

I'd say the reverse tolerance thing is still unproven - although I think a lot of people swear by it. It could just as equally be the ability to hold the smoke, or burn it the right way - to get the Salvinorin vaporised. I haven't seen any scientific work done on the subject so I'm staying sceptical about the whole thing.

I may be talking out my ass (just throwing ideas around), but I wonder if more receptors are made - and because there isn't a tolerance, it just enhances the effect, I think I read something about increase of receptors (adenosine?) that bind with caffiene, but it could just be me imagining (*Shrug*).

As for permanance I couldn't say. Sorry. Because there hasn't been a massive amount of research on salvinorin you may just have to do with refering to the behavior of other chemicals which have had more focus (dispite the obvious differences).

 

[gayedohi]

that makes sense, heat and hold do seem to have lot of influense thanks

 

[Dantediv86]

one thing i'm sure of
the tolerance (wether reverse or not) is a change in sensitivity of neurons to the substance you keep taking in (from my experience reverse tollerance is true and i had no idea it existed with salvia untill a week ago)
however if you stop taking the substance (whatever substance it might be) your body will fall back to the equilibrium after a certain time, so you'll start over again, hover this is true only to certain substances. alcohol has permanet sensitivity effects. my aunt can't drink a drop and she'll get drunk, and she was an alcoholic.

 

[gayedohi]

yes this seems to be the total opposite of acid where i have very high resistance. right now i have 6 grams of 20 x, i think i'll stock up on some 10x to bring with me to the wilderness.