Amphetamine effects: Less enjoyable the second time around?

[Skeetastic]

I used to use amphetamines (namely Adderall, amphetamine/dextroamphetamine) about 6 months ago, and the effects, when simply taken orally, were very enjoyable. But after a binge, and slight addiction, I went without for about 5-6 months. Just recently, I began to get back into them. However, I've found the same (or larger) doses, administered the same way, have less of an effect, and tend to keep me up late at night (or all night) all when 6 months earlier, they would at most keep me up til 2am. Can anyone explain this phenomenon?

 

[GOD]

I think its the same with most adictive drugs , after being adicted they dont do the same to me anymore and are not as enjoyable . Probably because your body has built up a tollerance to them and and antio bodys to deal with them , a bit like vacinating yourself .

 

[JustinNed]

Those are all basically just legal meth. To get a high from them try breaking them up and snorting them, or changing your dose higher.

Or just do the illegal substance and do some meth.

 

[Skeetastic]

Those are all basically just legal meth. To get a high from them try breaking them up and snorting them, or changing your dose higher.

Or just do the illegal substance and do some meth.

Even crushing and snorting it often isn't as good of a high. And I'm not gonna go near meth, I've seen what it can do to people (not the "faces of meth", but an actual friend of mine).

 

[Skeetastic]

I think its the same with most adictive drugs , after being adicted they dont do the same to me anymore and are not as enjoyable . Probably because your body has built up a tollerance to them and and antio bodys to deal with them , a bit like vacinating yourself .

Thing is though, I have friends who have done worse binges, gone without for a while, and restart with no problems like I've had. Plus, wouldn't a tolerance be decreased (or eliminated) after 6 months of keeping off of the substance?

 

[GOD]

I can only talk for me . Taking things that i`ve been adicted to doesnt work the same way as before i was adicted . And once you are vacinated your body knows how to build anti bodys and deal with chemicals . But everyone is different . Another thing is that drugs dont work the same when you get older from my experience , especialy with acid , and thats the experience of all the other old acid heads i know to .

 

[HeartCore]

Amphetamines suck.

Why do they keep coming up on a site about psychonautics. There is nothing psychonautic about amphetamines except for the Iboga you may use to get rid of the addiction

 

[Meduzz]

Amphetamines suck.

Why do they keep coming up on a site about psychonautics. There is nothing psychonautic about amphetamines except for the Iboga you may use to get rid of the addiction

and apart from being a chemical basic sceleton for other psychoactives...

And I'm not gonna go near meth

imho, you already are :wink:

 

[JustinNed]

Let me point out that meth is short for methAmphetamine
As God said, everyone is different, try a version of the pill that you haven't done before, there are 100's of different variations.

 

[Skeetastic]

Let me point out that meth is short for methAmphetamine
As God said, everyone is different, try a version of the pill that you haven't done before, there are 100's of different variations.

I'm aware of that. But I just don't wish to go to methamphetamine. Amphetamine isn't the same, albeit the same chemical family. Closely related, but still different.

 

[spice]

Seconding what Heartcore said- They suck.

Methamphetamine is VERY closely related to amphetamine, just smoother and stronger, but the mechanism of their addictiveness is EXACTLY the same. You are splitting hairs.

Also, welcome to the world of biochemistry....your biochemistry is unique. Just because your friends react to speed that way doesn't AT ALL mean you will....for the most part I find what GOD said to be true.
Dabbling with amphetamines as you are I doubt you've seen the real negative face of it.

It's not pretty.

I consider all non-psychoactive drugs that are popular such as speed and opiates as dominator drugs, per McKenna, and see absolutely no reason why they should be propagated.

There are a lot of interesting substances out there, some moreso than others, but they're all more promising than boring old speed.

Psychedelics have the opposite effect, they get BETTER as time goes by, and they're not addictive.

Also, chemically Adderall is a racemic mixture of three different types of amphetamine salts, and the reason for this is one that may surprise you;

Since adderall is prescribed for ADD/ADHD, the amphetamine level must remain elevated in the blood for extended periods of time; your body would normally detox a single salt form of amphetamine much quicker than adderall doses, so in this light, adderall is seen for what it REALLY IS; a time release form of amphetamine.

If meths effects are just longer duration and a stronger rush,
you're halfway there already and didn't even know it.

You're playin' with fire, man.

 

[Entheonaut]

Amphetamines suck.

Why do they keep coming up on a site about psychonautics. There is nothing psychonautic about amphetamines except for the Iboga you may use to get rid of the addiction

MDMA
3,4-MethyleneDioxyMethAmfetamine

Also sucks? :wink:


Spice:
Isn't aderall methylphenidate? I remember most ADD/ADHD medicines are methylphenidate.

 

[Entheonaut]

After thinking a little more about this: Aderall contains 4 amfetamine salts, so that's different than methylphenidate... But methylphenidate contains an amfetamine-group, but the whole molecule is quite different. It also contains a carboxylic acid-group (COOH). Does this mean it is defined as an amfetamine/amphetamine analog, or not?

Excuse my curiousity

edit: I see it's an ester now, not carboxilic acid

 

[phalaris]

Ritaline(tm)
methylphenidate:

You can see the basic amphetamine structure in methylphenidate.

By the way, my guess of the reason why methylphenidate acts relatively short (3-4 hours) as compared to amphetamine is due to the scission of the ester group (the big thing at the top of the molecule). The ester ( carboxylic acid coupled to an alcohol, in this case methanol) apparantly can cross cross the blood/brainbarrier, and the free carboxylic acid derivative cannot.


Amphetame:

Meth-ampetamine:

Adrenaline:
(all natural drug : )

...but the really interesting stuff is: can the methylphenidate be use as a backbone for an empathogenic or psychedelic series ? The 'MDMA' version for example may proof to be nice. In my experience the amphetamine component in MDMA goes on forever even when the the typical effects have worn off. A substance with a more defined peak of both the emphatogenic and speedy effect would be desirable in my opinion: lack of sleep is the real killer.

 

[Brugmansia]

You have used it many times in a row, the positive boost or high won't occur. But the side effects such as restlessness never fade away, on the contrary, they may get a hell.

Amphetamine, tend to have long after effects as well when the high is already over for a long time.

I have snorted dextro-amphetamine and it was nothing like amphetamine, I never got energetic on dextro-speed (appeltjespep in Nederlands), but an excessive long duration of clearness and concentration followed. But no need to move or dance.

I also had no jaw tension. I could simply write for ages on my keyboard with no sounds whatever around me.

The half-life value of dextro-speed is excessive, I turned normal 24 hours after my last two dots on a car key.

Somehow it was fairly easy to consume food, although there was no appetite, but no rejection of food either way.

The only thing I could appreciated a bit, was feeling relaxed/clam but never an unfocussed moment.

But it = wack. Speed kills. Dot.

 

[GOD]

I agree about MDMA , after a while it just made me strung out , something like coke , without the coke " nicenes " .To me speed was a tool to keep me awake , it never gave me any " pleasure " at all , in fact it made every other drug not work and they and life became boring . The only time that speed was interesting (???) for me was after 3 or 4 days awake i started having wierd gray halucinations = speed psychosis .

Speed is a waste of time .

 

[Jeer]

I consider all non-psychoactive drugs that are popular such as speed and opiates as dominator drugs, per McKenna, and see absolutely no reason why they should be propagated.

All drugs are psychoactive

 

[spice]

That's your opinion.

 

[Guest]

Opium is nice though, that 1 time in the year the poppies grow outside 8)
Far better then Amphetamines (IMHO)

 

[phalaris]

Opium is nice though, that 1 time in the year the poppies grow outside
Far better then Amphetamines (IMHO)

Yes, opium is nice when smoked. It is also very suitable in a social setting, chasing the dragon with a few friends. And, as you mentioned, is does not come along very often because it is season bound. Taking it orally can be somewhat tricky, as I learned from getting very sick and nausated (bucket next to my bed...). The next day I felt like shit, and my muscles ached.

But how can we compare amphetamine with opium ? To me it sounds like trying to compare a fishing boat to a Honda CRX.

Benzedrine is just another tool in my toolbox, but do I take it out frequently ? No. I love getting enough sleep more.

Also within the psychonaut community there are taboos, amphetamines are one of them.