The difference is in how and which receptors on our cells these substances are affecting.. alo the doses are different and the timing of the effects.
DMT is most simlar to the serotonin of the brain. That's why the intensity of it's effects is the strongest one, especialy when is smoked..
but than it's for short time, because DMT is easily destroyed in the body.
(this can be changed after combinig it with MAO-inhibitor(s) but only after special diet.
Mushrooms are almost the same , the diference is that their psyloci(bi)ne is oraly active , and maybe because of that- most popular in the humanity's past and present.
LSD has the smallest "doorstep" dose, and the smallest active dose. It affects several kind of receptors, not only the serotonine ones.
LSA is almost same in structure, but is about 10 times less active.
Both of these has longer effect than the tryptamines(7-12 hurs)
the effect is somehow similar not only to the tryptamines, but to the big groop of psychedelics, foun in the
Cati(phenetil-amines)
there are many different kinds of cati, and almost all of them contains many different phenetilamines and other psychoactive substances.
The Mescaline and the Peyote(Lophophora w.) are most /popular/well studied.
The effects aof the mescaline are even longer (about 20 hours) but not so intense, and the "doorstep" dose required is much higher.
The Salvia Divinorum is realy weard, it's even shorther than DMT but it's even more shocking, it's active dose is jus a bit bigger than the active dose of LSD and breakthrougs in completly other states of understandig are posible, but many people often find it a bit "too much".
(it is the most " similar to dying"expirience I've ever had)
All of these I've tryied, and liked DMT most,
Meskaline is also great, but it's so BITTER!
mushrooms is what I use most (about 7 times per year)
p.s.
DXM I've never tryied and I do not want to.
Iboagine is what i'm searcing for
This substance affects four or five different kinds of receptors and causes up to 3 day long trip..
and about the taste- mushrooms are great when mixed with honey and cacao.
Mescaline has much more shocking taste.
what I do not like about LSD is the doubts it bring on the next day.
no doubt about DMT thow.. - it's realy "OMG"