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I've heard two things regarding the safety of psychedelics.
1. No data on long term negative effects. If anything, there are positive effects in terms of anxiety.
On the other hand, I heard another thing the other night from Dr. Drew Pinksy from loveline. That is:
2. ALL psychadelics...
What worked for me is ingesting the capsules slowly. Shoot to take a capsule or two periodically over the span of almost two hours, and you'll probably be able to keep it down.